In the 1990's we made quite a lot of money via government contracts. We were paid to assess needs supply equipment and provide training in its use and our clients were blind and VI people at work. In 1998 I nearly died and came to realize we should be providing assistive technology etc for the majority who had no work or support. We struggled with a low cost option and came to realize it should be free. So we now seek commissions and contracts and a few charitable donations and have over a quarter of a million users round the world in eleven languages. We will never make a load of money this way but our sales and contract work gives us a decent way of life. We turn over around $2000 per year and give work to three blind people. We promote ourselves on the web and have learned to manipulate the meta tags to attract would-be users or their supporters.
For years I worked as an employee mainly for blindness organisations. It's a great feeling to use your own skills, make your own decisions and mistakes and not to be involved in stuff you are not enthusiastic about. Margaret, my wife, and I work together mainly from home and we enjoy much happiness from what we do and from the people we meet.
Try to work for and learn from someone in your line of business and then take courage and set up in opposition. Only do something you enjoy.